The IndeePlus 448KHZ is an innovative and versatile FDA-approved aesthetic device that utilizes Proionic® Radio Frequency, which offers rapid and deep penetration into the skin at 448kHz frequency. It is designed for facial and body enhancements, including skin tightening, cellulite reduction, body contouring, and reducing inflammation and pain for post-surgery recovery. The machine incorporates RF diathermy, vacuum therapy, and capacitive cupping to stimulate skin cells and promote various rejuvenating effects. For facial treatment, the device helps increase collagen synthesis, reduce fine wrinkles, improve eye bags and dark circles, provide facial rejuvenation, and reduce double chin. The treatment protocol typically involves 6 sessions lasting around 40 minutes each, with sessions scheduled 1-2 weeks apart. For body treatment, the device works to rebalance cell ion exchange, increase metabolism, rejuvenate skin tissue, and reduce fat, cellulite, and loose skin. The device offers several advantages, such as automatic adjustment of depth of action and energy flow, various sized treatment heads, real-time perception of body circuit impedance, and an intuitive touchscreen user interface for easy navigation and adjustment of settings. The treatment course usually involves 5-6 or 8-10 sessions, depending on the indications and individual patient needs. Treatment sessions can be undertaken 1 to 2 times a week, and there are no limitations as the 448kHz radiofrequency is harmless to the human body and its tissues.   Possible side effects may include redness and tingling in very sensitive skin, although the treatment is generally non-invasive and pleasant without adverse effects. Contraindications for the treatment include having a pacemaker or other electronic implants, pregnancy, non-intact skin (open wounds or burns), and thrombophlebitis.