Introducing the PINXEL-V portable microneedle fractional radio frequency machine, which is the latest generation of vacuum advanced microneedle technology. The machine combines the advantages of microneedling and radio frequency (RF) therapy with vacuum function to enhance local penetration and provide effective treatment for various skin problems. The beauty of the vacuum function is that it creates channels through the microneedles and delivers radiofrequency energy, pushing topical medication deeper into the skin. When the needle is retracted, air is released onto the skin, pushing the topical medication deep into the dermis. This resulted in a 67% increase in the local penetration of M and F needles. One of the main features of PINXEL-V is its stepper motor type, which ensures a smooth insertion of the needle without causing any shock, bleeding or pain after the procedure. The needle depth control can precisely target the epidermis and dermis, the range is 5-4.0mm, and the step size is 0.2mm. The needle itself is gold-plated, making it durable and highly biocompatible. Even patients with metal allergies can use it without worrying about contact dermatitis. The machine also features a safety needle system with sterilized disposable needle tips and LED lights to indicate application of RF energy. PINXEL-V offers insulated and non-insulated pin options. Insulated needles are less painful and treat only the dermis, reducing redness and speeding up recovery time. This model is suitable for those who need to go to work every day. On the other hand, non-insulated needles provide better results, but can be slightly more painful. They treat both the dermis and epidermis, resulting in longer recovery times and scab formation. This mode is ideal for those who prioritize achieving the best possible results. In addition to the microneedle RF therapy device, PINXEL-V is also equipped with a fractional RF therapy device. This applicator is designed for non-invasive wrinkle removal for patients who are afraid of needles. It offers similar benefits to Microneedling RF Therapy, but does not require any downtime, allowing for faster recovery. PINXEL-V is also available in mono/bipolar modes, allowing energy delivery at different depths. In bipolar mode, 50% of the needle is positive and the other 50% is negative, directing energy to the depth of the needle. This mode is more suitable for facial care. In mono mode, all needles on the tip are positive and the client holds the negative handle during treatment. This configuration allows the RF energy to penetrate deeper into the skin, making it more suitable for body treatments. Overall, the PINXEL-V Portable Microneedling Fractional RF Machine is a versatile and advanced tool for customizing treatments for all skin types, on any part of the body, at any time of the year. It combines vacuum, microneedling and radiofrequency technologies to provide enhanced topical penetration, preci